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Question

Acromegaly is caused by-


A

excess of thyroxine

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B

excess of STH

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C

excess of adrenaline

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D

deficiency of thyroxine

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Solution

The correct option is B

excess of STH


The correct option is B.

Explanation of correct option:

  1. Somatotrophic hormone (STH) is secreted by the anterior lobe of the pituitary gland.
  2. Acromegaly is a type of hormonal disorder that is caused by excess secretion of STH in adults.
  3. People suffering from acromegaly have enlarged bones on the face and limbs, increased BMR and heart rate, etc.
  4. Acromegaly can lead to premature death if left untreated.

Explanation of incorrect option:

Option A:

  1. Excess secretion of thyroxine leads to hyperthyroidism or Graves' disease.
  2. It is characterized by an enlarged thyroid gland, abnormal protrusion of eyeballs, increased BMR, weight loss, etc.

Option C:

  1. The adrenal medulla secretes two hormones- adrenaline and noradrenaline. These hormones are secreted in response to stress and emergency situations.
  2. Excess secretion of adrenaline can be a sign of adrenal tumor.

Option D:

  1. Deficiency of thyroxine results in hypothyroidism.
  2. Hypothyroidism causes an enlargement of the thyroid gland which is commonly known as goiter.

Final answer

Acromegaly is caused by an excess of STH.


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