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Question

How does cytochrome c carry electrons?


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Solution

Cytochrome C:

  1. Cytochrome c is a water-soluble protein that transports electrons and is found in the mitochondrial inner membrane.
  2. It has a heme iron metal center, which is required for its function in the ETC.

Cytochrome C electron transfer:

  1. The ETC transfers an electron from Complex III to the heme Fe3+ of oxidized cytochrome c, reducing it to Fe2+.
  2. Cytochrome c now transfers the electron to Complex IV.
  3. Cytochrome c is a movable electron carrier that aids in electron transfer from complex III to complex IV.
  4. Cytochrome c accepts electrons from complex III, which acts as an electron donor.
  5. Then it moves to complex IV, where cytochrome c is oxidized, releasing an electron into it.
  6. ATP is an energy currency that serves as fuel for the cell's operation.
  7. Cytochrome c is required for the ETC to function properly and produce ATP.
  8. Because of the presence of the haem group at its center, it can carry out various redox reactions that result in electron transport.
Loss of Function of Cytochrome c in Jurkat Cells Undergoing Fas-mediated  Apoptosis* - Journal of Biological Chemistry

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