Question

How glucose enters TCA cycle?

Answer 1

Glucose enters the TCA cycle:

1. The TCA cycle, also known as the Tricarboxylic Acid Cycle, is a set of chemical events that occur in all aerobic organisms' cells to release energy stored in the form of ATP through the conversion of Acetyl CoA generated from carbs, lipids, and proteins.
2. The Citric Acid Cycle, as it is sometimes called, occurs in mitochondria during the second phase of cellular respiration. Soluble enzymes catalyze the processes in the TCA cycle.
3. The linking process catalyzed by the pyruvate dehydrogenase complex connects glycolysis with the TCA cycle. Pyruvic acid, which is formed at the conclusion of glycolysis, is transported to the mitochondrial matrix, where it is oxidatively decarboxylated to create acetyl CoA.
4. The TCA cycle starts with acetyl CoA. In this process, two molecules of pyruvic acid created by the breakdown of a glucose molecule yield two molecules of acetyl CoA, carbon dioxide, and NADH.