CameraIcon
CameraIcon
SearchIcon
MyQuestionIcon
MyQuestionIcon
1
You visited us 1 times! Enjoying our articles? Unlock Full Access!
Question

How is acetyl CoA transported out of mitochondria?


Open in App
Solution

Mitochondria

  1. It is the powerhouse of the cell, mitochondria are double-bound organelle found in eukaryotic organisms.
  2. They are found inside the cytoplasm and help in digestive function.
  3. They play a major role in breaking down nutrients and generating energy-rich molecules for cells.
  4. The cristae and the proteins of the inner membrane aid in the production of ATP molecules.

Acetyl CoA transported out of mitochondria:

  1. Acetyl CoA can not cross the mitochondrial membrane.
  2. It is the forerunner of HMG CoA which consists of cholesterol and ketone bodies.
  3. Acetyl CoA is produced in the mitochondria by oxidative decarboxylation of pyruvate or oxidation of fatty acids.
  4. When the body is having excess ATP the energy is stored in the form of fatty acids.
  5. Hence the acetyl CoA enters the TCA cycle.
  6. If there is sufficient energy then the acetyl CoA is utilized in the fatty acid biosynthesis.
  7. Fatty acid biosynthesis occurs in the cytosol, so acetyl CoA has to be transported to the cytosol from the mitochondria.
  8. As it can not cross the membrane, it is transported out of mitochondria as citrate.
  9. Citrate is formed by the condensation of acetyl CoA with oxaloacetate by the enzyme citrate synthase.
  10. After reaching cytosol, citrate is converted back to oxaloacetate and acetyl CoA is released.

flag
Suggest Corrections
thumbs-up
6
Join BYJU'S Learning Program
similar_icon
Related Videos
thumbnail
lock
The Mitochondria
BIOLOGY
Watch in App
Join BYJU'S Learning Program
CrossIcon