Recombination is the exchange of genetic information between two chromosomes or between two parts of the same chromosome. Recombination is mainly of four types:
- Homologous recombination – occurs during meiosis, when a part of the chromosome is exchanged between two homologous chromosomes.
- Non-homologous recombination – exchange of genetic information between dissimilar chromosomes.
- Site-specific recombination – used in recombinant technology, DNA is cut at a specific site using restriction enzymes and a new piece of DNA is inserted, e.g. plasmid, bacteriophage, etc.
- Replicative recombination – E.g. A new copy of a transposable element is generated at a new site in the same chromosome.
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