Question

What do you mean by homologous recombination?

Answer 1

Homologous recombination:

1. The exchange of genetic information between two similar or identical strands of a double stranded DNA molecule is known as homologous recombination.
2. Homologous recombination plays an important role in the repairing of damaged DNA.
3. The damaged DNA strands undergo recombination during mitosis and repairs the injury.

Applications of Homologous recombination:

1. Creating recombinant DNA in genetically modified organisms i.e. gene targeting.
2. In protein engineering for the formation of new proteins.
3. In cancer therapy by helping the DNA damage to repair.