What Factors Govern The Rate Of Cell Division?

The pace of cell division is regulated by a combination of extracellular and intracellular factors. Yeast proliferation is limited primarily by external nutrient levels, which can vary widely in the wild. On the contrary, animal cells are normally bathed in regular high concentrations of nutrients, and their proliferation depends on both tissue-specific genetic programming and signals rendered by extracellular proteins generated by other cells. In early embryos, for example, extracellular and intracellular developmental patterning signals influence the rate of cell division in different regions. Extracellular proteins that stimulate cell division are known as mitogens.

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