ADH, also known as vasopressin, is a non-peptide produced in the hypothalamus.
It is crucial in the regulation of the body's osmotic equilibrium, blood pressure management, salt homeostasis, and kidney function.
ADH largely impacts the kidney's capacity to reabsorb water.
When ADH is present, it increases water reabsorption by inducing the production of water transport proteins in the late distal tubule and collecting duct.
Dehydration activates certain vascular receptors, signaling brain centers to begin drinking and ADH release.
Baro/volume receptors in the kidney help to stimulate the release of the enzyme renin, which starts a chain reaction that results in the production of angiotensin II, which also causes drinking and ADH release.