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Question

What happens to excess acetyl CoA?


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Solution

Acetyl CoA:

  1. Acetyl CoA is an important metabolism molecule, used in various biochemical reactions like protein, carbohydrates, and lipids metabolism.
  2. It is produced in mitochondria via fatty acids metabolism and oxidation of pyruvate to acetyl CoA.
  3. It's main function is to provide energy to the cells by entering the Kreb's cycle and producing ATP by oxidative phosphorylation.
  4. When there is an excess of fatty acids present, the amount of Acetyl CoA produced due to fatty acids metabolism increases.
  5. The excess of Acetyl CoA is then converted into ketone bodies.
  6. These can be circulated in the body.

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