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Question

What increases gluconeogenesis?


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Solution

Gluconeogenesis:

  1. The biochemical process of preparing glucose from the non-glucose sources within the cells is called gluconeogenesis.
  2. Glucose can be formed through amino acids, fatty acids, lactate as well as other non-carbohydrate sources.
  3. It occurs when the body is deficient in glucose. Thus, it is an energy-saving rather energy-producing process that occurs anaerobically.
  4. This process is significant since it leads to the synthesis of glucose which is the only source of nutrition for the brain.
  5. Pyruvate carboxylase, PEP carboxykinase, fructose 1,6-bisphosphatase, and glucose 6-phosphatase are the enzymes unique to gluconeogenesis.
  6. Gluconeogenesis occurs in the liver and kidneys.
  7. Hormones such as glucagon, glucocorticoids, etc. stimulate gluconeogenesis.

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