What Is the Smallest Unit of Chromosome?

The smallest unit of the chromosome is a nucleosome. It is made up of DNA wound around histone proteins. It is 10 nm in diameter. There is a core of 8 histone proteins and DNA is coiled around it. Each nucleosome contains around 200 bp of DNA. Two nucleosomes are attached by linker DNA. Nucleosomes further condense to form chromatin fibres, which further compact and form chromosomes.


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