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Question

What Is the starting material for glycolysis?


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Solution

Glycolysis:

  1. Glycolysis is a series of reactions that occurs when glucose molecules split into two 3-carbon molecules known as pyruvates, which then release energy in the form of ATP.
  2. Starting material for glycolysis is glucose.

Glycolytic pathway:

  1. To release ADP, ATP transfers its phosphate group to glucose. Glucose-6-phosphate is now formed from glucose.
  2. The isomer fructose-6-phosphate is formed from glucose-6-phosphate.
  3. ATP adds a phosphate group to fructose-6-phosphate, resulting in fructose-1,6,-biphosphate. Phosphofructokinase catalyzes this step of the pathway. It is an enzyme that regulates the glycolytic pathway's speed.
  4. Fructose-1,6-bisphosphate is then broken down into two 3-Carbon sugars. These are dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate isomers.
  5. DHAP is converted to glyceraldehyde-3-phosphate. These two are then in a state of equilibrium.
  6. When glyceraldehyde-3-phosphate is oxidized, NAD+ is reduced to NADH and H+. This is an exergonic, or energy-releasing, process. This energy then phosphorylates the molecule, resulting in 1,3-diphosphoglycerate.
  7. One phosphate group is released by 1,3-diphosphoglycerate, which is then added to ADP to form an ATP molecule. Following that, a molecule of 3-phosphoglycerate is formed.
  8. 3-phosphoglycerate is converted to 2-phosphoglycerate.
  9. 2-phosphoglycerate degrades into phosphoenolpyruvate after releasing a molecule of H2O. (PEP).
  10. PEP now emits a phosphate group, which joins with ADP to form ATP. PEP is converted into pyruvate, the end product of glycolysis.

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