B Cells and T Cells

Q. The cell mediated immunity inside the human body is carried out by :

1. T-lymphocytes
2. B-lymphocytes
3. Thrombocytes
4. Erythrocytes

Q. What is true about T - lymphocytes in mammals?

1. There are three main types cytotoxic T - cells, helper T - cells and suppressor T - cells
2. These originate in lymphoid tissues
3. These are produced in thyroid
4. They scavenge damaged cells and cellular debris

Q. Which of the following areas in the lymph node is regarded as thymus-dependent and thymus-independent area?

1. Medulla and paracortex region respectively
2. Cortex and paracortical region respectively
3. Medulla and cortex region respectively
4. Paracortical and cortex region respectively

Q. Cellular barriers

a) Provide acquired immunity
b) Provide non specific type of immunity
c) Are a type of leucocytes
d) Are phagocytic in nature
e) Produce interferons

Select the options that are incorrect with respect to cellular barriers

1. a, c, e
2. only a
3. a, d, e
4. a, e

Q.

how does B cells direct humoral immunity

Q. Which of the following is true about T-cells

1. T-cell based immunity that targets the cells and the intracellular pathogen is known as ‘Cellular Immunity’.

2. T-cells do not produce antibodies
3. T-cells recognize host cells that have been invaded by the pathogen
4. All of the above

Q. Explain the relationship between B-lymphocytes and T-lymphocytes in developing an immune response. [2 Marks]

Q.

What are CD4 lymphocytes?

Q.

B cells can produce antibodies specific to a particular antigen.

1. True

2. False

Q. _______test is based on the principle of antigen-antibody interaction.

1. DNA fingerprinting
2. ELISA
3. PCR
4. All of these

Q.

Antibody-mediated immunity is also known as _________

1. Humoral immunity

2. Innate immunity

3. Cell mediated immunity

4. Adaptive immunity

Q. Given below are a few statements related to SCID. Pick out the statement that doesn’t relate to it.

1. It is caused due to deficiency of the enzyme adenosine deaminase
2. It results in the lack of both B - cells and T - cells
3. It leads to the accumulation of homogentisic acid in the body
4. The number of circulating thymocytes are low

Q. Which blood cells can engulf bacteria by phagocytosis?

1. Eosinophil and Basophil
2. Neutrophil and Monocyte
3. Basophil and Lymphocyte
4. Neutrophil and Lymphocyte

Q.

How do B cells create antibodies?

Q.

B cells can produce antibodies specific to the particular antigen

1. False

2. True

Q. Bile pigments are the excretory products excreted by the lungs.

1. True
2. False

Q. What is true for monoclonal antibodies?

1. These antibodies obtained from one parent and for one antigen
2. These obtained from different parents and for one antigen
3. These obtained from many parents and for many antigen
4. These obtained from one parent and for many antigens

Q.

T cells kill cancer cells in the same way as they kill virus infected cells

1. True

2. False

Q. Which of the following thymus compartment is less populated with thymocytes?

1. Cortex
2. Medulla
3. Outer compartment
4. Middle compartment

Q. The letter T in T - lymphocyte refers to :

1. Thalamus
2. Tonsil
3. Thyroid
4. Thymus

Q. Given below are a few statements related to SCID. Pick out the statement that doesn’t relate to it.

1. It is caused due to deficiency of the enzyme adenosine deaminase
2. It results in the lack of both B - cells and T - cells
3. It leads to the accumulation of homogentisic acid in the body
4. The number of circulating thymocytes are low

Q. The lymphocytes capable of producing antibodies and can capture circulating antigens are known as

1. T-lymphocytes
2. B-lymphocytes
3. Large granular lymphocytes
4. T-helper cells

Q. Monoclonal antibodies(MAB) are produced from the hybrid cells of B-lymphocytes and myeloma cells. They are used?

1. In the preparation of vaccines
2. As immunosuppressant's
3. In the preparation of toxoids
4. For the detection of DNA probes

Q.

State whether true or false:
T cells kill cancer cells in the same way as they kill virus-infected cells.

1. True

2. False

Q. T-lymphocytes are

1. Formed in thymus
2. Formed in bone marrow and mature in thymus
3. Formed in thymus and preprocessed in bone marrow
4. Formed and preprocessed in bone marrow

Q. T cells are the immune cells responsible for self and non self recognition.

1. True
2. False

Q. Kohler and Milstein developed biotechnology for production of

1. Modern vaccines
2. Immobilised enzymes
3. Monoclonal antibodies
4. Myelomas

Q. Bring out the differences between B - lymphocytes and T - lymphocytes.

Q. Differentiate between.
Antibodies and interferons

Q. what are b and t lymphocytes and macrophages and what role do they have in this chap ter