Innate Immunity Barriers

Q. Match the following examples with their respective types of barriers:

Column I	Column II
A. Saliva	i. Physiological
B. Leukocytes	ii. Physical
C. Mucus	iii. Cytokine
D. Interferons	iv. Cellular

1. A $\to$ i, B $\to$ iii, C $\to$ ii, D $\to$ iv
2. A $\to$ ii, B $\to$ iii, C $\to$ i, D $\to$ iv
3. A $\to$ i, B $\to$ iv, C $\to$ iii, D $\to$ ii
4. A $\to$ i, B $\to$ iv, C $\to$ ii, D $\to$ iii

Q. Match column I (Types of T-cells) with column II (Function) and select the correct option.

Column I	Column II
A. Helper T cells	1. Directly attack and kill a cell
B. Cytotoxic T cells	2. Prevent attacking own cell
C. Suppressor T cells	3. Prevent exaggerated immune response
D. T delayed hypersensitivity cells	4. Activation of B cells

1. A - 4, B - 1, C - 2 and D - 3
2. A - 3, B - 1, C - 4 and D - 2
3. A - 2, B - 3, C - 4 and D - 1
4. A - 2, B - 4, C - 1 and D - 3

Q. Which of the following statements regarding different barriers of innate immunity is not correct?

1. Mucus membrane lining the respiratory, gastrointestinal and urogenital tracts helps in trapping the microbes and constitute physiological barriers of our body
2. Certain types of leucocytes such as polymorpho-nuclear leucocytes (PMNL-neutrophils) and lymphocytes such as natural killer cells, constitute cellular barriers of our body
3. Virus infected cells secrete proteins called interferons which protect non-infected cells from further viral infection and constitute cytokine barriers of our body
4. Acid present in the stomach, saliva in the mouth, tears from the eyes prevent the growth of microorganisms and constitute physiological barriers of our body

Q.

The cells involved in inflammatory reactions are:

1. Basophils

2. Eosinophils

3. Neutrophils

4. Lymphocytes

Q. A person without thymus would not be able to

1. reject a tissue transplant
2. receive a tissue transplant
3. develop an inflammatory response
4. produce antibodies

Q. Barrier created by saliva and tears is related to

1. Physical barriers
2. Cellular barriers
3. Physiological barriers
4. Cytokine barriers

Q.

Name the following:

Chemicals released by mast cells during an allergic reaction.

Q. PMNL are____(i)____barriers that provide__(ii)____immunity.

1. (i)-cytokine, (ii)-acquired
2. (i)-cellular, (ii)-acquired
3. (i)-cytokine, (ii)-innate
4. (i)-cellular, (ii)-innate

Q. Which of the following statements regarding different barriers of innate immunity is not correct?

1. Acid present in the stomach, saliva in the mouth, tears from the eyes prevent the growth of microorganisms and constitute physiological barriers of our body
2. Mucus membrane lining the respiratory, gastrointestinal and urogenital tracts helps in trapping the microbes and constitute physiological barriers of our body
3. Certain types of leucocytes such as polymorpho-nuclear leucocytes (PMNL-neutrophils) and lymphocytes such as natural killer cells, constitute cellular barriers of our body
4. Virus infected cells secrete proteins called interferons which protect non-infected cells from further viral infection and constitute cytokine barriers of our body

Q. Identify and select the wrong option regarding the four humors in our body as per good humor hypothesis?

1. 
   Blood
   
2. Phlegm
3. Yellow bile
4. Mucus

Q.

List the factors on which treatment of allergy depends upon

Q. Which one of the following acts as a physiological barrier to the entry of micro-organisms in the human body?

1. Tears
2. Skin
3. Lymphocyte
4. Monocyte

Q.

The antibody mediated Immunity, through antibody Production, inside the human body is carried out directly by_____________.

Q. Which of the following statement(s) about cellular barriers is correct?
I) Provide acquired immunity
II) Provide non specific type of immunity
III) Are a type of leukocytes
IV) Are phagocytic in nature
V) Produce interferons

1. I. II & V
2. Only I
3. II, III & IV
4. I & V

Q. A person without thymus would not be able to

1. reject a tissue transplant
2. receive a tissue transplant
3. develop an inflammatory response
4. produce antibodies

Q. Differentiate between.
Cellular immune response and humoral immune response

Q. Identify and select the wrong option regarding the four humors in our body as per good humor hypothesis?

1. 
   Blood
   
2. Phlegm
3. Yellow bile
4. Mucus

Q. In old age, problems like indigestion, constipation and gases are caused because of

1. Number of taste buds decreases
2. Muscular strength reduces
3. Amount of digestive juices decreases
4. All of the above

Q. Shot / Long answer type questions.
The barriers in the innate immunity are given in the following table. Identify a, b, C, and d.

	Type of barrier		Barrier
(i)	physical	(a)	skin
(ii)	physiological	(b)	in the eye
(iii)	tears	(c)	interferon
(iv)	cellular	(d)	WBC

Q. What do you understand by Immune System? Describe two main types of immune responses.

Q. A drop of perspiration was introduced into a nutrient medium. After incubation for 24 hours, the total bacterial count was checked and it was found to be negligible compared to the bacterial count in the tap water. This is due to the presence of:

1. Lipase
2. Lysozyme
3. Protease
4. Sodium chloride

Q. Differentiate between the following and give examples of each Innate and acquired immunity

Q. Assertion :Histamine is involved in allergic and inflammatory reactions. Reason: Histamine is a vasodilator.

1. Both the assertion and the reason are true and the reason is the correct explanation of the assertion.
2. Both the assertion and the reason are true and the reason is not the correct explanation of the assertion.
3. The assertion is true but the reason is false
4. Both the assertion and reason are false

Q. To which type of barries under innate immunity, do the saliva in the mouth and the tears from the eyes, belong?

1. Physiological barriers
2. Physical barriers
3. Cytokine barriers
4. Cellular barriers

Q. Innate immunity is provided by ___.

1. Antibodies
2. Neutrophils
3. T-cells
4. B-cells

Q. How do cellular barriers and cytokine barriers provide innate immunity in humans?

Q. Which one of the following acts as a physiological barrier to the entry of micro-organisms in the human body?

1. Tears
2. Skin
3. Lymphocyte
4. Monocyte

Q. Assertion :Passive immunity depends upon readymade antibodies. Reason: Passive immunity is of short life span.

1. if both Assertion and Reason are true and Reason is the correct explanation of Assertion
2. if both Assertion and Reason are true but Reason is not the correct explanation of Assertion
3. if Assertion is true but Reason is false
4. if both Assertion and Reason are false

Q. Mention three types of Innate barriers of defence with an example each.

Q. Write a brief note on humoral immunity?