Coagulation Cascade

Q.

During blood coagulation, the conversion of inactive fibrinogen to fibrin threads and the conversion of prothrombin to thrombin are catalysed by:

1. Both the reactions are catalysed by thrombin

2. Both the reactions are catalysed by thrombokinase

3. Thrombin and thrombokinase respectively

4. Thrombokinase and thrombin respectively

Q. ___are needed for clotting or coagulation of blood.

1. Amino acids
2. Albumins
3. Fibrinogens
4. Globulins

Q. Which of these converts soluble fibrinogen into insoluble fibrin?

1. Thrombin
2. Thromboplastin
3. Prothrombin
4. Ca2+

Q. Sort the following clotting factors from top to bottom starting from the factor coming after thromboplastin:

1. Fibrinogen
2. Fibrin
3. Thrombin
4. Prothrombin

Q. Blood coagulation is initiated by

1. prothrombin
2. thrombin
3. fibrinogen
4. fibrin

Q. ________ are the blood cells, whose decrease in number can affect the clotting of blood.

1. Erythrocytes
2. Leucocytes
3. Thrombocytes
4. Both a and b

Q. Which of the following statements is/are correct?

1. Clotting factors are activated by the damaged tissue outside the blood vessel only
2. Prothrombin is the inactive form of thrombin that is present in the plasma
3. The platelets outside the damaged blood vessel also activate a cascade of clotting factors
4. All of the above

Q. Vitamin K during blood coagulation is required for

1. change of fibrinogen to fibrin
2. change of prothrombin to thrombin
3. formation of prothrombin
4. all of the above

Q. Which ion is required for the coagulation of blood?

1. Zinc
2. Copper
3. Magnesium
4. Calcium

Q. The process to stop the flow of blood is called

1. erythropoiesis
2. hematopoiesis
3. coagulation
4. hemostasis