The correct option is C Cell mediated immune response
A grafted kidney may be rejected in a patient due to cell-mediated immune response that is mediated by T- lymphocytes.
The body has the ability to differentiate self and non-self. Therefore, the matching of tissues and blood groups is essential before performing a graft or transplant.
Even after a transplant, the patients are given immuno-suppressants for a long span of time, to avoid the risk of rejections.