Question

A person is born with a hereditary disease with a weakened immune system due to deficiency of an enzyme. Identify the deficient enzyme and explain the technique used for cure. [2]

Answer 1

The person suffers from ADA (Adenosine Deaminase) deficiency. It is caused due to the deletion of the gene that codes for ADA. ADA is an enzyme which is crucial for the functioning of the immune system. [1]
If the gene for producing ADA is isolated from donor marrow cells and introduced into cells at early embryonic stages, it could be a permanent cure for this disease. [1]