Question

Alloxan treatment destroys

• A. STH cells
• B. Sertoli cells
• C. Leydig's cells
• D. $\beta$- cells of islets of Langerhans

Answer 1

The correct option is D $\beta$- cells of islets of Langerhans

A. STH or somatotropin hormone is known as growth hormone and stimulates body growth and carbohydrate, protein, fat metabolism.

B. Sertoli cells are part of seminiferous tubules and help in spermatogenesis (production of sperms from germ cells) as they provide nourishment to the developing sperms.

C. Leydig cells, also known as interstitial cells are present in the testis near seminiferous tubules. They secrete testosterone hormone which helps in the development of secondary sexual characteristics in males.

D. ββ-cells of islets of Langerhans are part of pancreas and secrete insulin hormone which regulate blood glucose levels.

Alloxan is a toxic analogue of glucose which destroys insulin producing cells of pancreas i.e. ββ-cells of islets of Langerhans.

So, the correct answer is 'ββ-cells of islets of Langerhans'.