Question

Assertion [A]: Glucagon is said to lower the blood sugar level.

Reason [R]: Glucagon increases the utilization of glucose in the tissues and glycogen in liver.

• A. Assertion [A] is True and Reason [R] is False.
• B. Reason [R] is True and Assertion [A] is False.
• C. Assertion [A] is True and Reason [R] is True and is a correct explanation to [A].
• D. Assertion [A] is True and Reason [R] is True but is the incorrect explanation to [A].

Answer 1

The correct option is B

Reason [R] is True and Assertion [A] is False.

Glucagon increases blood sugar level and insulin reduces it. They are antagonistic pancreatic hormones. Glucagon is a peptide hormone, and plays an important role in maintaining normal blood glucose levels. Glucagon acts mainly on the liver cells (hepatocytes) and stimulates glycogenolysis (forming glucose from the breakdown of glycogen) resulting in an increased blood sugar (hyperglycemia). In addition, this hormone stimulates the process of gluconeogenesis which also contributes to hyperglycemia. Glucagon reduces the cellular glucose uptake and utilisation. Thus, glucagon is a hyperglycemic hormone. Insulin is the hormone responsible for the entrance of glucose from blood into cells. When glucose levels are low, for example, during fasting, glucagon is secreted and insulin is inhibited. When glucose levels are high, like after meals, glucagon is inhibited and insulin secretion is increased.