Question

Choose the correct answer from the alternatives given :
In one polynucleotide strand of a DNA molecule the ratio of A + T/G + C is 0.3. What is the A + G/T + C ratio of the entire DNA molecule?

• A. 0.3
• B. 0.6
• C. 1.2
• D. 1

Answer 1

Answer: (D)

1

According to Chargaff's rule (1950), purine and pyrimidine base pairs are present in equal amounts in a DNA molecule.
i.e. [A + G] = [T + C]
or $\frac{[A+C]}{[T+C]}=1$