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Question

Cross bridges of sarcomere in skeletal muscle are made up of 


A
Actin
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B
Myosin
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C
Troponin
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D
Tropomyosin
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Solution

The correct option is B Myosin
  • Active sites for myosin (Thick filament) are present on actin which are masked by troponin in resting state. when  Ca++ level increases it leads to the binding of calcium with a subunit of troponin on actin(thin) filaments and thereby remove the masking of active sites for myosin.
  • Utilizing the energy from ATP hydrolysis, the myosin head now binds to the exposed active sites on actin to form a cross bridge. thus myosin forms cross bridges.
  • This pulls the attached actin filaments towards the centre of ‘A’ band.
  •  The ‘Z’ line attached to these actins are also pulled inwards thereby causing a shortening of the sarcomere, i.e., contraction.
  • Hence cross bridges of sarcomere in skeletal muscle are made up of myosin.
  • So, the correct answer is 'Myosin'.

Biology

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