During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure. What is its DNA-binding sequence?
A
TATA
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B
TTAA
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C
AATT
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D
CACC
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Solution
The correct option is A TATA TATA box is a DNA sequence that is present in the promoter region of the DNA of eukaryotes and some archaea. The TATA box usually contains the sequence TATA and followed by a variable sequence. During transcription, the RNA polymerase holoenzyme recognizes the TATA sequence in the promoter, binds to it and initiates transcription.