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Question

Exchange of segments between non-homologous chromosomes is

A
Translocation
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B
Inversion
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C
Crossing over
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D
Tetrasomy
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Solution

The correct option is A Translocation
1) Translocation: a chromosome translocation is a chromosome abnormality caused by rearrangement of parts between non-homologous chromosome. A segment from one chromosome is exchanged with a segment from another non-homologous one, so two translocation chromosomes are generated simultaneously. The exchange of chromosome parts between non-homologous establishes new linkage relations.
2) An inversion is a chromosome rearrangement in which a segment of a chromosome is reversed end to end. An inversion occurs when a single chromosome undergoes breakage and rearrangement within itself.
3) Crossing over is the exchange of genetic material between non-sister chromatids of homologous chromosomes during meiosis, which results in new allelic combinations in the daughter cells.
4) A tetrasomy is a form of aneuploidy with the presence of four copies, instead of the normal two, of a particular chromosome.

So, the correct answer is 'Translocation'.

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