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Question

Glucagon is secreted by___ cells of pancreas.


Solution

Glucagon is a peptide hormone, secreted by alpha cells of the iselt of langerhans in pancreas. It plays an important role in maintaining blood glucose levels. Glucagon acts mainly on the liver cells (hepatocytes) and stimulates glycogenolysis resulting in an increased blood sugar (hyperglycemia). In addition, this hormone stimulates the process of gluconeogenesis which also contributes to hyperglycemia. Beta cells of pancreas secrete insulin which functions antagonistic to glucagon.

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