The correct option is A Estrogen
Graffian follicle
Mature ovarian follicles are called the Graffian follicle which rupture and releases the secondary oocyte.
Estrogen
Estrogen is secreted by the Graafian follicle present in the ovary. It increases the endometrial thickening in the uterus. A high amount of estrogen causes an LH surge resulting in ovulation.
Relaxin
Relaxin is secreted by the corpus luteum and the placenta. It relaxes the pelvic ligaments helping in childbirth.
Progesterone
Progesterone is released by the corpus luteum and the placenta. This hormone helps in maintaining the thickness of the endometrium of the uterus thus helping in maintaining pregnancy.
Cortisone
Cortisone is a hormone produced by the adrenal cortex. Cortisone is used to reduce inflammation.
Hence, the correct answer is Estrogen