Question

If the oxyntic cells of gastric glands are rendered non-functional then which of the following process is/are affected

• A. Digestion of proteins in alkaline medium
• B. Absorption of vitamin B12
• C. Digestion of starch
• D. Igestion of fats by lingual lipase

Answer 1

Answer: (B)

Absorption of vitamin B12

Functions of Oxyntic/Parietal cells :

1)It secretes Hydrochloric Acid (HCl) which sterilizes the food and activates the inactive proteolytic enzymes secreted in the stomach.

2)HCl, convert the Ferric form of Iron (+3) to Ferrous form of iron (+2)-absorbable form.

3)It secretes Castle Intrinsic Factor - required for active absorption of Vitamin B${}_1$${}_2$(Castle extrinsic factor) in intestine.

So, if Oxyntic cells of gastric glands are rendered non-functional then absorption of Vitamin B${}_1$${}_2$ will be affected.

Thus, the Correct answer to the question is 'Absorption of vitamin B${}_1$${}_2$'.