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Question

If the sequence of the coding strand in a transcription unit is written as follows
5' - ATGCATGCATGCATGCATGCATGCATGC - 3'
Write down the sequence of mRNA.

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Solution

If the coding strand in a transcription unit is
5’- ATGCATGCATGCATGCATGCATGCATGC-3’
Then, the template strand in 3’ to 5’ direction would be
3’ – TACGTACGTACGTACGTACGTACGTACG-5’
It is known that the sequence of mRNA is same as the coding strand of DNA. However, in RNA, thymine is replaced by uracil. Hence, the sequence of mRNA will be

5’- AUGCAUGCAUGCAUGCAUGCAUGCAUGC-3’


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