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Question

In eukaryotic transcription
(A) RNA polymerase II is responsible for the transcription of hnRNA
(B) The transcription factors recognise the promoter
(C) The core promoter determines the frequency of initiation
(D) Transcription termination by genes transcribed by RNA polymerase I are similar to rho-dependent prokaryotic termination

Choose the correct option

A
A, B, and C
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B
A, B, and D
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C
B, C, and D
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D
A, C, and D
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Solution

The correct option is B A, B, and D
Transcription in eukaryotes is initiated with the help of transcription factors responsible for recognising the promoter, to which the RNA polymerase binds, which determines the transcription start point. The sequence elements upstream of the core promoter influence the frequency of initiation.

In eukaryotes, transcription termination is different for different RNA polymerases. RNA polymerase I transcription termination is similar to rho-dependant termination in prokaryotes. The ribosomal rRNA genes transcribed by RNA Polymerase I contain a specific sequence of base pairs that is recognized by a termination protein called TTF-1. This is similar to the rho-dependent termination in prokaryotes.

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