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Question

In response to experimental results concerning IBMX, Snyder et al contended that it is not uncommon for psychoactive drugs to have


  1. Mixed effects on the brain.

  2. Close structural relationships with caffeine.

  3. Inhibitory effects on enzymes in the brain.

  4. The ability to dislodge caffeine from receptors in the brain.


Solution

The correct option is A

Mixed effects on the brain.


The effects of IBMX are discussed in the last paragraph of the passage.

IBMX apparently binds to adenosine-specific receptors on neuronal membranes but in contrast to the other caffeine derivatives that Snyder et al experimented with. IBMX depresses rather than stimulates mouse locomotion.

Snyder et al respond to this experimental result by stating that IBMX has "mixed effects on the brain, a not unusual occurrence with psychoactive drugs".

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