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Question

In the tissues, a high concentration of carbon dioxide

A
increases the affinity of haemoglobin to both oxygen and hydrogen ions.
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B
increases the affinity of haemoglobin to oxygen but decreases its affinity to hydrogen ions.
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C
decreases the affinity of haemoglobin to oxygen but increases its affinity to hydrogen ions.
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D
decreases the affinity of haemoglobin to both oxygen and hydrogen ions.
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Solution

The correct option is C decreases the affinity of haemoglobin to oxygen but increases its affinity to hydrogen ions.
In the tissues, high concentrations of carbon dioxide decreases the affinity of haemoglobin to oxygen so that it can dissociate. It increases the affinity of haemoglobin to hydrogen ions, so it can remove the excess of hydrogen ions from solution, which are formed when the carbon dioxide reacts with water and forms carbonic acid.

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