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Question

It is well known that Queen Victoria of England was a carrier for haemophilia. She married an unaffected male and since this is an X-linked disease, it can be predicted that

A
all her sons had the disease
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B
all her daughters had the disease
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C
both her parents had the disease
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D
haemophilia would have occurred more in her male descendants than her female descendants
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Solution

The correct option is D haemophilia would have occurred more in her male descendants than her female descendants
Queen Victoria of England was a carrier of haemophilia. It is an X-linked disease so if both her parents had the disease then she will also be affected and will not be carrier.
Queen Victoria married an unaffected normal male and produced nine children. Only one of her son was affected and 2 other daughters were carriers.
Further it can be observed that Queen Victor has four grandsons, and six or seven great-grandsons and possibly a great-granddaughter were afflicted with hemophilia.
So we can conclude that haemophilia occured more in her male descendants than her female descendants.

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