Question

Mature Graafian follicle is generally present in the ovary of a healthy human female around:

• A. 18– 23 day of menstrual cycle
• B. 24– 28 day of menstrual cycle
• C. $11–17$ day of menstrual cycle
• D. $5–8$ day of menstrual cycle

Answer 1

The correct option is C $11–17$ day of menstrual cycle

Follicular phase of menstrual cycle :

During the $6-13$ days of the cycle, the level of follicle stimulating hormone ($FSH$) keeps increasing and stimulates the development of the Graafian follicle. The developing Graafian follicle continues to release increasing levels of oestrogen which promotes the thickening and proliferation of the uterine lining. This is known as the follicular phase. By the end of this phase the Graafian follicle is fully matured.

Ovulatory phase of menstrual cycle :

The ovulatory phase generally takes place around day $14$. Increased levels of estrogen released by the mature Graafian follicle results in a surge in the level of Luteinizing hormone released from the anterior pituitary. This causes the Graafian follicle to rupture and release the ovum from the ovary (ovulation).

Luteal phase of menstrual cycle :

The luteal phase includes days $15to28$.The ruptured Graafian follicle changes to corpus luteum which releases progesterone. In case no fertilisation occurs, the corpus luteum degenerates in a few days. The uterus continues to thicken in anticipation of receiving a fertilised egg.

Final answer

Option b.