Metallic ions required for formation of haemoglobin are
A
Fe++ and Cu++
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B
Fe++ and Co++
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C
Fe++ and Zn++
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D
Both A and B
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Solution
The correct option is C Both A and B Hemoglobin is a protein found in the red blood cells, contains Fe (iron) and serves as the principal transporter of molecular O2 in the blood. There are two major parts of haemoglobin:
1) Haeme: a porphyrin with a Fe in the centre.
2) The second part of the haemoglobin is the globin. Globin is the protein (polypeptide) surrounding the haeme. Cobalt and nickel are essential trace elements with significant impact on the processes of hematopoiesis stimulation of erythropoietin production and haemoglobin synthesis. Copper-containing enzymes like cytochrome-c oxidase help in iron metabolism, the formation of haemoglobin, and mechanisms of hematopoiesis.