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Question

Oxygen haemoglobin dissociation curve will shift to right on decrease of


A
Acidity
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B
Carbon dioxide concentration
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C
Both A and B
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D
pH
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Solution

The correct option is D pH
A decrease in pH (increase in $$H^+$$ ion concentration) shifts the standard curve to the right, while an increase shifts it to the left. This occurs because at greater $$H^+$$ ion concentration. So, with increased acidity, the haemoglobin binds less $$O_2$$ for a given $$PO_2$$ (and more $$H^+$$). This is known as the Bohr effect.

Biology

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