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Question

Read the given paragraph and select the option that correctly fills the blanks in it.
Hormones produce their effect on target tissue by binding to specific _________A called hormone receptors located in the target tissues only. Water soluble hormones usually need _________B receptor that generate _________C messengers for regulating cellular metabolism. __________D soluble hormones can pass through cell membrane and bind to _________E receptors, mostly nuclear receptors. The hormone receptors complex enter the nucleus and mostly regulate gene expression or chromosome function by interaction of hormone-receptor complex with the genome.

A
A-proteins, B-membrane bound, C- second, D- lipid, E-intracellular
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B
A-lipids, B-membrane bound, C-second, D-water, E-intracellular
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C
A-proteins, B-intracellular, C-second, D-lipid, E-extra cellular
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D
A-proteins, B-membrane bound, C-primary, D-lipid, E-intracellular
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Solution

The correct option is A A-proteins, B-membrane bound, C- second, D- lipid, E-intracellular
Hormones produce their effect on target tissue by binding to specific proteins called hormone receptors located in the target tissues only. Water soluble hormones usually need membrane-bound receptors that generate second messengers for regulating cellular metabolism. Lipid soluble hormones can pass through the cell membrane and bind to intracellular receptors, mostly nuclear receptors. The hormone-receptor complex enters the nucleus and mostly regulate gene expression or chromosome function by an interaction of the hormone-receptor complex with the genome.
Thus, the correct answer is 'A-proteins, B-membrane bound, C- second, D- lipid, E-intracellular.'

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