Second generation vaccine is

Small pox vaccine

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DPT vaccine

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Hepatitis B vaccine

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Polio vaccine

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Solution

The correct option is C Hepatitis B vaccine
Vaccines which are developed from the recombinant DNA technology are called as second generation vaccines. It is developed to reduce the risks from the live vaccines which were earlier used for the prevention of the diseases Hepatitis B vaccine is an example of the second generation vaccine.
Thus, the correct answer is option C.

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__ first developed a vaccine against Small pox.

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