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Question

Sister chromatids separate during

A
prophase
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B
metaphase
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C
anaphase
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D
telophase
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Solution

The correct option is C anaphase
Mitosis is a type of cell division during which there is division of the nucleus followed by division of cytoplasm.

In interphase, the DNA associated with histone proteins forms into dense string-like fibres called chromatin.

During the prophase stage of mitosis, the chromatin undergoes coiling and packaging to form into compact, short structures known as chromosomes. The chromosomes then align in the centre of the cell and spindle fibres attach to the chromosomes.

The centromere holding the sister chromatids splits and the chromatids separate. These separated chromatids are pulled to opposite poles by spindle fibres. This occurs during anaphase.

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