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Question

The association of histone H1 with a nucleosome indicates :

A
Transcription is occurring
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B
DNA replication is occurring
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C
DNA is condensed into a chromatin fibre
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D
DNA double helix is exposed
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Solution

The correct option is C DNA is condensed into a chromatin fibre
The negatively charged DNA is wrapped around the positively charged histone octamer to form a nucleosome.
The H1 protein binds to the "linker DNA" region between nucleosomes. This association of H1 with the nucleosome packs the DNA into chromatin fibers.


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