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Question

The "cos" in cosmid comes from?

A
Cos sites in yeast
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B
Cos sites in bacteria
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C
Cos sites of plasmids
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D
Cos sites in phages
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Solution

The correct option is D Cos sites in phages
To overcome the small insert size of plasmids, scientists came up with cosmids. These are modifications of the phage genome. Most commonly used are the M13 and Lambda phage. Cosmids have the cos sites from phages and all other viral genes are removed.

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