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Question

The length of DNA molecule greatly exceeds the dimensions of the nucleus in eukaryotic cells. How is then the DNA accommodated inside the nucleus?

A
Deletion of non-essential genes
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B
Super-coiling in nucleosomes
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C
DNAase digestion
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D
Through elimination of repetitive DNA
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Solution

The correct option is A Super-coiling in nucleosomes
  • DNA is too lengthy hence kept as condensed, super-coiled, and wrapped around histones proteins as nucleosomes in chromosomes.
  • Supercoiling of DNA reduces the space and allows for much more DNA to be packaged inside nucleus.

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