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Question

The oxygen dissociation curve shifts to the right when


A

partial pressure of CO2 decreases

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B

partial pressure of CO2 increases

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C

partial pressure of O2 decreases

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D

pH of blood increases

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Solution

The correct option is B

partial pressure of CO2 increases


The strength with which oxygen binds to haemoglobin is affected by several factors. These factors shift or reshape the oxyhaemoglobin dissociation curve. A rightward shift indicates that the haemoglobin under study has a decreased affinity for oxygen. This could result from:
(i) an increase in partial pressure of carbon dioxide
(ii) an increase in acidity (decrease in pH) of blood
(iii) an increase in body temperature
(iv) an increase in 2,3-bisphosphoglycerate

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