The secretion of K+ by the distal tubule will be decreased by
A
Metabolic alkalosis
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B
A high K+ diet
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C
Hyperaldosteronism
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D
Spironolactone administration
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Solution
The correct option is C Hyperaldosteronism Hyperaldosteronism is a disease in which the adrenal glands make too much aldosterone which leads to hypertension (high blood pressure) and low blood potassium levels. A low blood potassium level would indicate a decrease in the secretion of K+ by the distal tubule.