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Question

Transition state structure of the substrate formed during an enzymatic reaction is:


A
Temporary but stable
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B
Permanent but unstable
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C
Temporary and unstable
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D
Permanent and stable
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Solution

The correct option is D Temporary and unstable
The substrates bind with enzymes to form an intermediate enzyme-substrate complex (also known as transition state). This complex/state is highly unstable and temporary. The complex dissociates to form the products.

E (Enzyme) + S (Substrate) → ES (Enzyme-Substrate Complex) → E (Enzyme) + P (Product)

Biology

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