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Question

Which is not a pharmaceutical product obtained through biotechnology?

A
Clotting factor
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B
Cholecystokinin
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C
Human insulin
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D
Human growth hormone
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Solution

The correct option is B Cholecystokinin
Insulin
Insulin is a peptide hormone produced by beta cells of the islet of langerhans present in the pancreas. It regulates the blood glucose levels by enhancing the uptake of glucose into the cells.
Recombinant insulin is produced by genetic engineering in Escherichia coli to treat patients having diabetes mellitus.

Clotting factor
Clotting factors refer to the peptides which help to promote blood clotting during injury. In haemophilia, gene encoding clotting factors VIII and IX are mutated leading to malformation. This results in heavy loss of blood even during minor injuries. Recombinant clotting factors are produced using biotechnological methods to treat haemophiliacs.

Cholecystokinin
Cholecystokinin is a peptide hormone secreted by enteroendocrine cells of the small intestine to stimulate the gallbladder to release stored bile juice into the duodenum for facilitating digestion of fats.

Recombinant cholecystokinin is used nowadays but it is not a pharmaceutical product.

Human growth hormone
Human growth hormone is a peptide hormone which stimulates the overall growth of the body by promoting cell division, cell differentiation. Recombinant human growth hormone is produced and given as a treatment to the people who have deficiency of growth hormone.

Final answer:
(c) Cholecystokinin


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