Which of the following characteristics is/are true regarding double stranded DNA?
a. Purine and pyrimidines are present in equal amount.
b. The bases of two strands are paired through hydrogen bonds.
c. Adenine is equimolar with guanine.
d. Phosphate group is linked to a nucleoside through N-glycosidic linkage.
[0.7 mark]

a, b and c

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a and b only

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b only

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b, c and d

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Solution

The correct option is B a and b only
In dsDNA, purines (adenine and guanine) and pyrimidines (cytosine and thymine) are present in equal amount. Complementary bases of the two strands are paired with hydrogen bonds.
In dsDNA, adenine is equimolar with thymine.
Phosphate group is linked with 5′ – OH of a nucleoside through phosphoester linkage.

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D N A

$I$	$I I$
$(a)$ Hydrogen bond	$(i)$ Adenine - deoxyric base
$(b)$ N-glycosidic linkage	$(i i)$ Glucose - Fructose
$(c)$ Phosphodiester bond	$(i i i)$ Leucine - Glycine
$(d)$ Peptide bond	$(i v)$ Nucleotide - Nucleotide in polynucleotide chain
	$(v)$ Guanine - Cytosin on opposite strands of DNA

How many guanine found in double stranded DNA that has 700 hydrogen bonds and 10% adenine

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