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Question

Which of the following factors is not favourable for the formation of oxyhaemoglobin?

A
High pO2
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B
Low temperature
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C
Less H+ concentration
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D
High pCO2
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Solution

The correct option is A High pCO2
Following are the four factors that are responsible for the oxyhaemoglobin in alveoli:
pO2:The greater the partial pressure of the oxygen causes the binding of hemoglobin with the oxygen efficiently.
Temperature: The normal temperature favors the binding of hemoglobin with oxygen. The high temperature is responsible for the dissociation of the oxygen from haemoglobin.
pCO2: The large amount of the carbon dioxide decreases the formation of the oxyhaemoglobin. The carbon dioxide has more affinity for haemoglobin than with the oxygen.
H+: The increase in the hydrogen ion concentration or decrease in pH causes the increases in the dissociation of haemoglobin.
Thus, a high pCO2 is not favourable for the formation of oxyhaemoglobin.
So, the correct answer is (D).

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