Question

Which of the following factors is not responsible for the denaturation of proteins?

• A. Heat
• B. low pressure
• C. pH change
• D. None of the above

Answer 1

The correct option is B low pressure

When protein in native form is subjected​ to a physical change like temperature or ​pH, the hydrogen bonds are disturbed. As a result, globules get unfold ​and helices get uncoiled therefore,​proteins lose its activity.​
During denaturation $2^o$ and $3^o$ structures get destroyed but $1^o$ structure remains the same.​
Example:

1. Coagulation of egg ​while on boiling.​
2. Curdling of milk caused by ​bacteria present in milk.