Question

Which of the following statement does not appropriately substantiate the concept of RNA being the initial genetic material?

• A.
  Self splicing property of RNA molecule
• B. Involvement of molecules like NAD or FAD in the process of ATP synthesis
• C.
  Involvement of enzyme primase in DNA replication
• D. Phosphorylation of creatine to form high energy creatine phosphate molecule

Answer 1

The correct option is A

Self splicing property of RNA molecule
RNA is the first genetic material in cells because: RNA is capable of both storing genetic information and catalyzing chemical reactions. Essential life processes like metabolism, translation, splicing, etc. evolved around RNA.

a) The RNA is cut and spliced together by a spliceosome, a molecular machine composed of protein and RNA. It is a process where newly made precursor messenger RNA transcript is transformed into a mature messenger RNA.

b) NADH will directly feed into the respiratory chain to propel mitochondrial ATP synthesis.

c) DNA primase is an enzyme involved in the replication of DNA and is a type of RNA polymerase. Primase catalyzes the synthesis of a short RNA (or DNA in some organisms) segment called a primer complementary to a ssDNA (single-stranded DNA) template.

d) Nucleotides are also the essential building blocks for the synthesis of DNA and RNA.

So, the incorrect statement is 'Self splicing property of RNA molecule'.