Which of the follwing would help accomplish the following conversion in a single step:
A
Dissolved metal reduction
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B
Catalytic hydrogenation with Pt
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C
Catalytic hydrogenation with Lindlar Pd/C
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D
Catalytic hydrogenation with Raney Nickel
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Solution
The correct option is D Catalytic hydrogenation with Lindlar Pd/C Observe that the substrate has a triple bond between carbons 2 and 3 which becomes a cis configuration double bond in the product. Also, there is the small aspect of a hydroxyl acid becoming a lactone.