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Question

Which one of the following is used as a vector for cloning of genes into higher organisms?

A
Retrovirus
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B
Baculo virus
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C
Salmonella typhimurium
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D
Rhizopus nigricans
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Solution

The correct option is A Retrovirus
  • A retrovirus is a single-stranded RNA virus that stores its nucleic acid in the form of an mRNA genome and targets a host cell as an obligate parasite.
  • Once inside the host cell cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern.
  • Thus, retroviruses function differently - their RNA is reverse-transcribed into DNA, which is integrated into the host cell's genome, and then undergoes the usual transcription and translational processes to express the genes carried by the virus.
  • These are used as a vector for the cloning of genes into higher animals.

So, the correct answer is option A.

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